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Old 5th September 2018, 12:15 AM   #1 (permalink)
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The Mechanism by which Exercise prevents Heart Attack in the Long Run.

The Mechanism by which Exercise prevents Heart Attack in the Long Run.

Originally Posted by Ender (HWZ)
Thread title: 46yo man died after completing SAFRA Bay Run Army Half Marathon
It's not to cure heart attack lah. It's to prevent or minimize blood clot after the plaque raptures. The plaque is caused by cholesterol. Aspirin is to thin the blood to prevent the clot. The clot obstruct blood flow.
Ultimately what it does is it tries to prevent a full blown heart attack when early onset of symptom is detected.
I think the CORRECT APPROACH is regular exercise. Exercise is a SPECIAL SITUATION when the heart beats hard n fast, endorphins and adrenaline are increased, arteries expand n become more elastic ... An orchestra of optimal, coordinated microscopic cellular level repair operations.

My suspicion is that exercise seems to set up the body (ESPECIALLY THE ARTERIES) and mind towards a reset and recovery mode.

During long sedentary periods, cholesterol will accumulate like plaster to (TEMPORARILY) patch holes (damage) in artery walls with the expectation that exercise will come along with the definitive repair/reset button to coordinate and organise all the essential ingredients (waste removal, nutrient supply, hormonal stimulus, cellular repair, smooth muscle stretching and activation, personality and mood improvement etc) towards making the artery wall elastic, smooth and new again (post exercise recovery and rebuilding period).

However, if no exercise session comes along, then the temporary measures just have to continue and in extremis (during prolonged sedentary periods and aggravated by smoking, diabetes, stress etc), calcium is added to stabilize the temporary repair cholesterol : unfortunately, these temporary repair methods ultimately will result in a spectacular breakdown at some point if allowed to accumulate indefinitely : it then becomes an unstable plaque which will precipitate a heart attack (myocardial infarction) if disturbed and the 'fibrous cap' allowed to burst and allow the accumulated pool of cholesterol to leak out.

Thus the best approach to heart attack / stroke prevention is to keep arteries elastic and supple by healthy lifestyle and regular exercise which is like kneading bread or mozzarella cheese : the more u knead, the more chewy the product is: which is how healthy arteries should be, not stiff, calcified and inflexible aka 'porcelain aorta'.

People need to do regular sessions of aerobic exercise to 'reset' the physiology of their arteries so that for life, their arteries will remain supple and young to efficiently supply steady blood pressure to the muscles etc, rather that porcelain / lead pipe aorta which CANNOT MODULATE blood pressure and thus contribute to more arterial damage, cholesterol problems etc etc.

The human body is like a nuclear reactor power station: both powerful yet fragile at the same time. Only vz healthy lifestyle and regular exercise will the 'reactor' continue to function without prematurely breaking down.

Your aspirin is a good try, but based on my hypothesis / explanation, your approach can best be categorized as 'too little and too late', once u have atherosclerosis /atheromas formed, u r a waiting time bomb and a disaster waiting to happen. And for those who have never exercised before, I guess their health is a train wreck in slow motion.

The best that one can do by the time atherosclerosis /atheroma formation has happened is to immediately adopt healthy lifestyle of sufficient rest, stress control, risk factors control (diabetes, hypy, cholesterol, smoking etc) while doing only very gentle exercise like walking to try to disperse(reverse) the cholesterol plaque without too much shear force as to tear open the fibrous cap. Guess if one were sedentary for 20years, then maybe only delicately increase the exercise heart rate intensity by say 1% max/ week at first and stop if just a bit unwell. It may take 10-20years to get back to fitness but at least one would not break open the fibrous cap and die whilst doing so (exercising).

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Caveat : the exercise must not be excessive and shouldn't result in any joint pains and just to be sure that it isn't excessive, one should feel totally ready to repeat the exercise session by day 3 after the day of exercise. (Doesn't mean must exercise on day3, just that full recovery shouldn't take more than 3 days to be considered 'not excessive exercise').

(Knowledge based on interest and self study).

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Last edited by BicCherry; 5th September 2018 at 12:23 AM.
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